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Promising new therapies for uterine fibroids. (Ultrasound Procedure).
VAIL, COLO. -- High-intensity focused ultrasound and gene therapy are two promising developments worth keeping an eye on for treatment of uterine fibroids, Dr. William D. Schlaff said at a conference on obstetrics and gynecology sponsored by the University of Colorado.
Myolysis, in contrast, is not. For a decade now, various investigators have pursued the goal of destroying fibroids by coagulating them via intramyomatous electrodes, lasers, or cryoprobes. The results have been singularly unimpressive, he said.
"I think we ought to bury myolysis," said Dr. Schlaff, professor and vice chairman of ob.gyn. and chief of reproductive endocrinology at the university.
In one version of the myolysis procedure, a bipolar needle is inserted into the fibroid, where it zaps roughly a 5-[mm.sup.3] area of tissue around the tip.
"A big fibroid 5 cm or more will require 50-75 punctures. That's a lot. Why not just take it out instead?" he asked.
The various clinical series reported to date indicate myolysis and cryomyolysis are distinguished by an unpredictable therapeutic response and significant short-term complications. There are essentially no long-term follow-up or quality of life data, he added.
High-intensity focused ultrasound (HIFU) utilizes an energy ...
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Source: HighBeam Research, Promising new therapies for uterine fibroids. (Ultrasound Procedure).