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Children born via in vitro fertilization are significantly more likely to be diagnosed with neurologic problems, especially cerebral palsy, said Dr. Bo Stromberg and associates at University Children's Hospital, Uppsala, Sweden.
These results "can largely be, though not solely explained by the high frequency of twins born, and by low birth weight, and low gestational age, but an effect of the in vitro fertilization [JVF] procedure per ... se cannot be excluded," the researchers said.
Detailed medical records allowed for a retrospective cohort study of 5,680 children born via [IVF] including 2,060 twins, and 11,360 controls, including 4,120 control twins.
The children, born between 1982 and 1995, were at least 18 months old at the time of neurologic follow-up, at which point 2% of all the IVF babies had been diagnosed with neurologic problems, compared with 1% of the control babies. However, only 1% of singleton IVF babies had neurologic problems, as did 1% of singleton control babies, Dr. Stromberg erg and his associates said (Lancet 359[9305]:461-65, 2002).
Although percentages of those diagnosed with a neurologic problem were similar when IVF ...