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Third-trimester nausea may flag acute fatty liver.(Obstetrics)
WASHINGTON -- Acute fatty liver of pregnancy must be ruled out in any woman who presents in the third trimester with nausea, vomiting, epigastric pain, or malaise, Michael F. Fesenmeier, M.D., said at the annual meeting of the Central Association of Obstetricians and Gynecologists.
The disorder is rare, estimated to affect only 1 in 7,000-16,000 pregnancies. But it is deadly. Maternal and neonatal mortality rates of 75% have been reported in some studies.
"Physicians must be diligent in diagnosing acute fatty liver of pregnancy, and be prepared for its high morbidity and mortality," said Dr. Fesenmeier of the University of Cincinnati Medical Center.
He and his associates assessed the clinical presentations and outcomes of all 16 women treated for acute fatty liver of pregnancy (AFLP) at three tertiary-care centers in Ohio and Kentucky between 1993 and 2003. The average gestational age at diagnosis was 35.2 weeks (range, 30.0-37.2 weeks). There were 13 singleton and 3 twin pregnancies.
Nausea and vomiting were the most common presenting symptoms, affecting 12 patients (75%). The average duration of nausea and vomiting before the women presented for emergency care was 3-4 days, but some women went undiagnosed for much ...
- Third-trimester nausea may point to acute fatty liver of pregnancy.(Women's...
- Magazine article from: Family Practice News Moon, Mary Ann March 1, 2005 700+ words
WASHINGTON -- Acute fatty liver of pregnancy must be ruled out...must be diligent in diagnosing acute fatty liver of pregnancy, and be prepared...outcomes of all 16 women treated for acute fatty liver of pregnancy (AFLP) at three...
- Gene defect perils mother and baby. (maternal acute fatty liver of pregnancy...
- Magazine article from: USA Today (Magazine) October 1, 1995 700+ words
...delivery of their babies. Following childbirth, most mothers fully recover. The cause of this rare illness, maternal acute fatty liver of pregnancy, is a genetic mutation inherited by the babies, researchers at Washington University School of Medicine...
- Preeclampsia easily confused with a wide range of syndromes: Acute Fatty Liver,...
- Magazine article from: OB GYN News Lippman, Helen January 15, 2002 700+ words
...delivery, while some of the conditions that mimic it are metabolic and many continue long after, he advised. * Acute fatty liver of pregnancy (AFL). This is a metabolic disorder that typically develops between 27 and 41 weeks' gestation...
- New fatty liver findings from Shandong University, Institute of Toxicology...
- Newspaper article from: Biotech Week December 24, 2008 700+ words
...data in the report 'The anti-fatty liver effects of garlic oil on acute...GO) on acute ethanol-induced fatty liver were investigated. Mice were...4.8 g/kg bw) to induce acute fatty liver," scientists in Shandong, People...
- Fatty liver may cause Third-Trimester nausea. (Triplet Pregnancies).
- Magazine article from: OB GYN News Walsh, Nancy February 1, 2002 700+ words
SARASOTA FLA. -- Think of acute fatty liver hen a woman with a triplet pregnancy...contrast, published reports of acute fatty liver during pregnancy suggest that...pregnancies are associated with acute fatty liver, and triplet gestation may...
- Fatty Liver Disease.(Liver Disorders)
- The Columbia Univ. Coll. of Physicians & Surgeons Complete Home Medical Guide LaPook, Jonathan January 1, 1995 700+ words
...presence of fatty deposits in a liver tissue sample. Acute fatty liver of pregnancy occurs in late pregnancy (after the...include abdominal pain, jaundice, and encephalopathy. Acute fatty liver of pregnancy is different from cholestasis of pregnancy...
- Fatty Liver
- Encyclopedia entry from: Gale Encyclopedia of Medicine, 3rd ed. Edgren, Altha January 1, 2006 700+ words
Fatty Liver Definition Fatty liver is the collection of excessive amounts of triglycerides and other fats inside liver cells. Description Also called steatosis, fatty liver can be a temporary or long-term condition, which is not harmful...
- Fatty liver disease on rise, can lead to cirrhosis, death.
- Newspaper article from: Knight Ridder/Tribune News Service Uhlenhuth, Karen June 16, 2003 700+ words
...high cholesterol _ add one more: fatty liver disease. The presence of too much fat...prevalent than we understood before." Fatty liver disease gained a name and definition...of Americans are afflicted with it. Fatty liver develops in an estimated 20 percent...
