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Antinausea drug appears safe in pregnancy.(Obstetrics)
Ondansetron is increasingly prescribed off label for nausea and vomiting in pregnancy, and a new study suggests it is safe for this indication.
In the prospective observational study, the drug, which is typically used for treating nausea and vomiting in cancer chemotherapy patients, was not associated with an increased risk of fetal malformations, reported Adrienne Einarson, R.N., of the University of Toronto and her colleagues (BJOG 2004;111:940-3).
The investigators studied women exposed to ondansetron (Zofran), other antiemetics (including Diclectin, metoclopramide, phenothiazines, ...
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