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DHEA supplementation may enhance benefits of exercise.(Clinical Rounds)
LISBON -- Dehydroepiandrosterone supplementation may enhance the glucose- and lipid-lowering effects of resistance exercise in women. Chia-Hua Kuo, Ph.D., reported at the 12th International Congress on Endocrinology.
The findings suggest that twice-daily doses of 25 mg dehydroepiandrosterone (DHEA)--sold over the counter as an "anti-aging" supplement--may be a clinically beneficial adjunct to physical activity in older populations, said Dr. Kuo of the Taipei Physical Education College, Taiwan.
Twenty healthy female subjects performed a single bout of exercise, consisting of 5 minutes of low-intensity stationary bicycling, followed by 60 minutes of high-intensity dynamic resistance exercise (including bench presses, leg extensions, and abdominal curls), and finally, another 5 low-intensity minutes on the bike.
Over the next 2 days, 10 of the subjects (mean age 39 years) were given 25 mg DHEA twice daily, and the other 10 (mean age 41) were given placebo supplements.
After 48 hours, blood levels of DHEA sulfate increased significantly from baseline--from 1,260 ng/mL to 3,790 ng/mL--in those who received the supplements, but did not change in the placebo subjects.
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Source: HighBeam Research, DHEA supplementation may enhance benefits of exercise.(Clinical...