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Metabolic syndrome linked to stroke risk.(Clinical Rounds)
ATLANTA -- Metabolic syndrome appears to confer a twofold increase in the risk of stroke, Xuejuan Jin, M.D., reported at a prevention conference on heart disease and stroke sponsored by the Centers for Disease Control and Prevention.
In an analysis of public data from the 1987-1989 Atherosclerosis Risk in Communities (ARIC) study, which included nearly 16,000 adults aged 45-64 years with no history of stroke, from four U.S. communities, the prevalence of metabolic syndrome was 32%. After adjustment for age, ethnicity, gender, education, cigarette smoking, LDL cholesterol, and coronary heart disease status, the risk for stroke associated with metabolic disorder was 2.1 times higher.
There was a strong dose-response relationship between the number of components of metabolic syndrome that a patient had and the risk of stroke during follow-up. Dr. Jin, of Pennsylvania State University, Hershey, reported in a poster.
Metabolic syndrome was defined in this study, according to National Cholesterol Education Program Adult Treatment Panel II criteria, as the presence of at least three of the following five metabolic syndrome components: ...
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