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Restless legs syndrome common in pregnancy.(Obstetrics)
Restless legs syndrome occurs in 26% of pregnancies, peaking in the 7th and 8th months but sharply declining around the time of delivery, an Italian study of more than 600 women revealed.
Although an association between restless legs syndrome (RLS) and pregnancy was first reported in 1940, a study by Mauro Manconi, M.D., of Vita-Salute University in Milan and associates is the first large epidemiologic study to explore the connection (Neurology 2004;63:1065-9).
The researchers concluded that pregnancy is an "important risk factor" for RLS and hypothesized that a pregnancy-related nocturnal increase in prolactin and associated reduction in dopaminergic activity may be to blame for cases that arise in pregnancy or are worsened by it.
A total of 606 women were interviewed within 2 days after parturition by one of two neurologists certified in sleep medicine about their medical and family histories, pregnancy histories, iron and folate therapy, sleep habits, and presence of sleep disorders. Follow-up interviews were conducted at 1, 3, and 6 months after delivery with 161 women who met international diagnostic criteria for RLS, including:
* Desire to move the limbs, usually associated with paresthesias/dysesthesias.
* Motor restlessness.
* Worsening of symptoms at rest, with at least partial and temporary relief by activity.
- Survey Shows That Nearly Two-Thirds of Americans are Not Aware of Restless Legs...
- Press release article from: PR Newswire September 20, 2004 700+ words
...evaluating patients' symptoms of RLS, it is important to rule out...are associated with secondary RLS symptoms, such as iron deficiency, pregnancy and renal failure. "By becoming...the condition, people with RLS symptoms can have a more productive...
- Requip(R) (Ropinirole HCl) Tablets First and Only Medication Approved By the...
- Press release article from: PR Newswire May 5, 2005 700+ words
...Moderate-to-Severe Primary RLS The approval of Requip for moderate...trials in adults diagnosed with RLS. Patients with RLS secondary to other conditions (e.g. iron deficiency, pregnancy and renal failure) were excluded...
- Leg Ailment Patients Might Get A Kick Out Of FDA Approval; Thumbs Up For Glaxo...
- Magazine article from: Investor's Business Daily May 23, 2005 700+ words
...Georgianna Bell, president of the RLS Foundation. "It affects quality...nobody knows exactly what causes RLS. It seems to run in families...diverse factors as anemia, pregnancy, neurological legions, kidney...patients with moderate to severe RLS and put them on a much lower...
- Treatment of restless legs syndrome with iron infusion therapy: this...
- Magazine article from: JAAPA-Journal of the American Academy of Physicians Assistants Gorder, Vicki Kuntz, Susan Khosla, Seema March 1, 2009 700+ words
...RLS. (5) People who develop RLS at a young age (less than 45...case, the primary etiology of RLS may include iron deficiency...of patients. (3) Secondary RLS can be associated with a variety...such as iron deficiency, pregnancy, renal failure, and repetitive...
- Restless Legs Syndrome (RLS) Foundation is the Preeminent Source of Unbiased,...
- Press release article from: PR Newswire June 22, 2005 700+ words
...editor, you may be interested in Restless Leg Syndrome (RLS), particularly now that the FDA has approved a drug for treatment of RLS. An estimated 10% of the U.S. population has RLS, yet many people suffer for years from misdiagnosis or...
- Genicon Sciences Launches RLS Two-Color Nucleic Acid Microarray Toolkit for the...
- Press release article from: Business Wire February 5, 2003 700+ words
...commercially available Resonance Light Scattering (RLS) Technology product -- an RLS-based Two-Color Nucleic Acid Microarray Toolkit...part of a fully integrated detection system, the RLS Array Detection System that provides researchers...
- In RLS, depression severity key when treating both.(Mental Health)
- Magazine article from: Family Practice News Worcester, Sharon September 15, 2006 700+ words
...depression have been shown to exacerbate RLS symptoms, said Dr. Winkelman, associate...presenting with untreated severe depression and RLS, treat the depression first. If possible...as bupropion instead, he advised. The RLS symptoms should be treated shortly thereafter...
- New National Survey Shows Restless Legs Syndrome (RLS) Is Largely...
- Press release article from: PR Newswire November 10, 2005 700+ words
...Organizations Call for More Education at RLS Foundation National Patient Meeting ORLANDO...not familiar with Restless Legs Syndrome (RLS), a chronic and disruptive neurological...percent of U.S. adults had not heard of RLS. While awareness of RLS is increasing...
- With comorbid RLS, severity of depression is key factor.(Psychiatry)(Report)
- Magazine article from: Internal Medicine News Worcester, Sharon October 1, 2006 700+ words
...depression have been shown to exacerbate RLS symptoms, said Dr. Winkelman, associate...presenting with untreated severe depression and RLS, treat the depression first. If possible...as bupropion instead, he advised. The RLS symptoms should be treated shortly thereafter...
- Requip(R) (ropinirole HCl) Tablets Significantly Improve Symptoms of Restless...
- Press release article from: PR Newswire January 3, 2006 700+ words
...U.S. Study in Moderate-to-Severe Primary RLS Published in Mayo Clinic Proceedings RESEARCH TRIANGLE...ropinirole HCl) Tablets significantly improve RLS symptoms. The study, entitled TREAT RLS US (Therapy with Ropinirole, Efficacy and Tolerability...
Source: HighBeam Research, Restless legs syndrome common in pregnancy.(Obstetrics)