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The first broad survey of maternal diet and how it might affect risk of acute lymphoblastic leukemia in children suggests that beans, beef, carrots, peas, and cantaloupe consumed during pregnancy may be protective.
Mothers of 138 children who developed acute lymphoblastic leukemia (ALL) at a mean age of 5 years and 138 matched controls from the same communities completed a survey that asked them about their diet during the year before their pregnancies, said Christopher D. Jensen, Ph.D., of the University of California, Berkeley, and his associates (Cancer Causes Control 2004;15:559-70).
The investigators did not ask about diet during pregnancy because diet can be affected by nausea and it varies by trimester. Diet before pregnancy, however, reflects the mother's nutritional adequacy at the start of pregnancy and her eating patterns, which generally do not change during pregnancy, Dr. Jensen said.
Evidence has accumulated in recent years to suggest that the initiating genetic event of childhood leukemia often occurs in utero, raising the question of whether there might be maternal environmental ...