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Plasma HPV DNA may be useful to monitor therapy and disease progression.

OBGYN & Reproduction Week

| November 22, 2004 | COPYRIGHT 2009 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2004 NOV 22 - (NewsRx.com & NewsRx.net) -- Measuring levels of human papillomavirus DNA in plasma of women with cervical cancer may be useful for monitoring response to therapy and disease progression, suggest researchers at the University of Hong Kong.

To evaluate the clinical usefulness of circulating DNA for cervical cancer management, H.J. Yang and colleagues quantified "DNA extracted from pretreatment plasma of 50 cervical cancer patients and from serial longitudinal plasma of 21 patients ... for HPV16/HPV18 by means of quantitative polymerase chain reaction. Another 15 patients with low-grade lesion (LG), 18 patients with high-grade lesion (HG), and 96 normal…

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