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SAN FRANCISCO -- Hysteroscopic metroplasty for hypoplastic uterus in 29 infertile women helped 21 of them achieve 30 pregnancies, resulting in 16 live births, Dr. Herve Fernandez said at the annual meeting of the American Association of Gynecologic Laparoscopists.
By comparison, before the surgical therapy, 26 pregnancies in these patients resulted in only one live birth at 29 weeks' gestation.
Four of the 16 babies born after hysteroscopic metroplasty were delivered preterm but all of them after 30 weeks' gestation, said Dr. Fernandez of AntoineBeclere Hospital, Paris.
The report represents the largest series of patients with hypoplastic uteri to undergo this treatment.
Hypoplastic uterus is a rare congenital malformation except in women who were exposed in utero to diethylstilbestrol (DES). The timing of medical use of DES--between 1955 and 1977--suggests that physicians now are seeing a peak ...