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Novel peptide-based vaccines generate immunity to hepatotropic pathogens.

Hepatitis Weekly

| November 01, 2004 | COPYRIGHT 2009 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2004 NOV 1 - (NewsRx.com & NewsRx.net) -- Novel peptide-based vaccines generate immunity to hepatotropic pathogens.

"Vaccines for the prophylactic and/or therapeutic immunization against hepatotropic pathogens (e.g., hepatitis B and hepatitis C virus) should establish long-lasting, specific antiviral effector/memory CD8+ T cell immunity in the liver," researchers in Germany report.

"We describe a novel peptide-based vaccine in which antigenic major histocompatibility complex class I-binding peptides are fused to a cationic (e.g., human immunodeficiency virus tat-derived) domain and complexed to immune-stimulating oligonucleotides. This vaccine formulation…

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Source: HighBeam Research, Novel peptide-based vaccines generate immunity to hepatotropic...

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