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Use of Depo-Provera was significantly associated with the development of cervical infections in a study of 819 women, said Charles S. Morrison, Ph.D.
Even after adjustment for sexual behavior and demographic traits including condom use and multiple sex partners, women who used Depo-Provera (medroxyprogesterone) were more likely to developed gonorrhea or chlamydia within a year, compared both with women who used oral contraceptives and controls, said Dr. Morrison of Family Health International, a research organization in Research Triangle Park, N.C.
The use of oral contraceptives was not associated with increased risk or development of infections.
After a mean follow-up of 337 days, 45 women in the prospective cohort study had developed at least one cervical infection.
Most of the women were single (77%) and nulliparous (75%). They ranged in age from 15 to 45 years, with a median age of 22 years (Sex. Transm. Dis. 31[9]:561-67, 2004).
The researchers calculated risk based on how many women became infected within a year (woman-years) ...
Source: HighBeam Research, Depo-Provera users appear to be prone to STDs: the use of oral...