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Chlorhexidine bests povidone iodine in small study.(Gynecology)
SAN DIEGO -- Chlorhexidine was more effective than povidone iodine in sterilizing the vagina before hysterectomy in a small, randomized study.
"We can't say that using chlorhexidine would lead to a reduction in infections following vaginal hysterectomy, but I think we can say that it is more effective than povidone iodine in decreasing bacterial colony counts," Dr. Patrick Culligan said at the joint annual meeting of the American Urogynecologic Society and the Society of Gynecologic Surgeons.
"By my way of thinking, this interventional change would be no more expensive and no more time consuming, and it seems to make the vagina cleaner for surgery," Dr. Culligan said.
For the study, he and his associates randomized 50 women who underwent vaginal hysterectomy between October 2002 and September 2003 to receive a surgical scrub with either povidone iodine or chlorhexidine. Standard prophylactic techniques were used for both groups, including preoperative intravenous antibiotics, said Dr. Culligan of the division of urogynecology at the University of Louisville (Ky.) Health Sciences Center.
Investigators obtained aerobic and anaerobic bacterial cultures of the ...
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