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Family history of breast cancer may increase adverse effects of stress.(Gynecology)
ORLANDO, FLA. -- Ordinary life stressors such as those experienced in the work place may be more detrimental to the health of women with a family history of breast cancer than to those with normal breast cancer risk, a recent study suggests.
In a study of 217 healthy women with a mean age of 36 years, timed sample collections of urine showed that cortisol levels were significantly higher at work among those with a first-degree relative diagnosed with breast cancer (25.28 ng/mL) than among those with no family history (19.75 ng/mL). Lucia Dettenborn reported during the annual meeting of the American Psychosomatic Society.
Those with a family history also had larger increases in urinary cortisol levels from baseline--the lowest level measured either at home or during sleep--to work (337%) than those with no family history of the disease (227%), said Ms. Dettenborn, who is a predoctoral student at Mount Sinai School of Medicine, New York.
Urine was collected during work hours (11 a.m. to 3 p.m.), home hours (6 p.m. to 10 p.m.), and sleep hours (10 p.m. to 6 a.m.).
There were no significant differences between the groups in end of day cortisol levels and in at home cortisol levels in this study.
Several studies have shown that women with a family history of breast cancer have increased general emotional distress as well as greater cancer-specific distress, such as recurring intrusive thoughts about breast cancer.
Previous studies also have shown that women with a family history of breast cancer ...
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Source: HighBeam Research, Family history of breast cancer may increase adverse effects of...