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Fetal nasal bone length shown to be independent of maternal factors.(Obstetrics)

OB GYN News

| October 01, 2004 | Brunk, Doug | COPYRIGHT 2004 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

PHOENIX -- A woman's ethnic origin, age, weight, and diabetic status do not significantly affect the rate of growth or length of her fetus's nasal bones, Dr. Ants Toi said at the annual meeting of the American Institute of Ultrasound in Medicine.

The medical literature is mixed on this topic with respect to the influence of ethnic origin. In one British study of nasal bone hyoplasia at 15-22 weeks' gestation as a marker for trisomy 21, whites had fewer hypoplastic nasal bones, compared with Afro-Caribbeans (Ultrasound Obstet. Gynecol. 21[1]:15-18, 2003).

Dr. Toi and associates evaluated 1,424 women aged 16-46 years with normal pregnancy outcomes who were referred to Mount Sinai Hospital, Toronto, for first-trimester aneuploidy screening between January 2002 and July 2003. They measured fetal nasal bone length and crown-rump length and recorded maternal characteristics, including self-reported ethnic origin, age, weight, and ...

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