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DNA vaccine protects mice against challenge anthrax STI spores.

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| October 18, 2004 | COPYRIGHT 2009 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2004 OCT 18 - (NewsRx.com & NewsRx.net) -- DNA vaccination protected mice against challenge with Bacillus anthracis STI spores.

According to published research from Germany, "Immune responses against the protective antigen (PA) of Bacillus anthracis are known to confer immunity against anthrax. We evaluated the efficacy of genetic vaccination with plasmid vectors encoding PA, in protecting mice from a lethal challenge with B. anthracis STI spores. BALB/c and A/J mice were immunized via gene gun inoculation, using eukaryotic expression vectors with different cellular targeting signals for the encoded antigen."

"The vector pSecTag PA83, encoding the full-length …

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Source: HighBeam Research, DNA vaccine protects mice against challenge anthrax STI spores.

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