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Study of 72 girls: reproductive organs larger in obese girls.(Gynecology)
NEW ORLEANS -- Childhood obesity has significant effects on ovarian and uterine morphology in prepubertal girls, Dr. Arlene Mercado said in a poster session at the annual meting of the Endocrine Society.
Dr. Mercado, a fellow at the National Institute of Child Health and Human Development in Bethesda, Md., said that increasing body mass index is associated with an increase in both uterine length and ovarian volume. These changes may be associated with precocious early puberty.
"We already know that low body weight is associated with late onset of puberty," Dr. Mercado said in an interview. "In this case, however, we think that adiposity increases the number of leptin receptors in the hypothalamus, which increases gonadotropin stimulating hormone, leading to an increase in circulating estrogen."
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Source: HighBeam Research, Study of 72 girls: reproductive organs larger in obese...