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Topical estrogen resolves labial adhesions in girls; avoiding surgery.(Gynecology)
PHILADELPHIA -- Labial adhesions in prepubertal girls were successfully treated with topical estrogen without the need for surgery in a series of 36 patients at a single center.
"Manual separation after thinning with estrogen cream is an excellent method for expediting resolution," Dr. Jane E. Dopkin said at a poster session at the annual meeting of the North American Society for Pediatric and Adolescent Gynecology.
The patient series re viewed by Dr. Dopkin and her associates included gifts who were diagnosed with labial adhesion from September 1999 to September 2002 at Cincinnati Children's Hospital Medical Center. The average age of the gifts was 4.8 years, with a range of 3 months to 11 years. At the time of referral, 44% of the gifts had a first episode; the rest had a history of adhesions. A total of 22% had symptoms, including dysuria, vulvar itching, odor, and discharge. Primary care providers had diagnosed 81% of the patients, and 75% had been treated with topical estrogen before referral.
All patients received a regimen of topical estrogen twice a day along with basic hygiene. The average time to resolution of the adhesions was 2.6 ...
- Even severe labial adhesions rarely need surgery: Topical estrogen effective....
- Magazine article from: Pediatric News Johnson, Kate August 1, 2001 700+ words
TORONTO -- Even severe labial adhesions in children can be successfully...Surgery is rarely necessary if topical estrogen is used appropriately...of 251 girls with severe labial adhesions, topical estrogen was successful in 91% of...
- Labial adhesions.(Disease/Disorder overview)
- Clinical Reference Systems Brayden, Robert January 1, 2006 700+ words
...called adhesions. Labial adhesions usually occur before...What is the cause? Labial adhesions are usually caused...are they treated? Topical estrogen creams can be applied...this treatment, labial adhesions return for many girls...
- Labial Adhesions.(Pediatric Advisor 2002.1)
- Clinical Reference Systems Brayden, Robert January 1, 2002 700+ words
...called adhesions. Labial adhesions usually occur before...What is the cause? Labial adhesions are usually caused...are they treated? Topical estrogen creams can be applied...this treatment, labial adhesions return for many girls...
- Labial Adhesions.(Pediatric Advisor 2004.1)
- Clinical Reference Systems Brayden, Robert January 1, 2004 700+ words
...called adhesions. Labial adhesions usually occur before...What is the cause? Labial adhesions are usually caused...are they treated? Topical estrogen creams can be applied...this treatment, labial adhesions return for many girls...
- Yale researchers create topical estrogen that alleviates sexual dysfunction in...
- Press release article from: M2 Presswire May 9, 2001 700+ words
...UNIVERSITY: Yale researchers create topical estrogen that alleviates sexual dysfunction...Yale researchers have created a topical estrogen that eliminates side effects of conventional...some symptoms of aging skin. "The topical estrogen we've created confines itself to...
- Topical Estrogen Replacement Therapy Accepted For Review.(Brief Article)
- Magazine article from: Women's Health Weekly October 4, 2001 700+ words
...Administration has accepted for review the New Drug Application (NDA) for Estrasorb (17-beta-estradiol) cream, a topical estrogen replacement therapy licensed to King by Novavax, Inc. Estrasorb employs Novavax's proprietary micellar nanoparticle...
- Topical Estrogen Replacement Therapy Accepted For Review.
- Newspaper article from: Biotech Week October 3, 2001 700+ words
...Administration has accepted for review the New Drug Application (NDA) for Estrasorb (17-beta-estradiol) cream, a topical estrogen replacement therapy licensed to King by Novavax, Inc. Estrasorb employs Novavax's proprietary micellar nanoparticle...
- Topical estrogen for postmenopausal women.(Consultation)
- Magazine article from: Clinical Advisor Stpyker, Morgan September 1, 2009 700+ words
...dementia. If atrophic vaginitis is the patient's primary complaint, topical rather than systemic estrogen is preferred. Topical estrogen is available ill cream, tablet, or ring formulations. Adding progesterone has been shown to decrease the risk of cancers...
