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ATLANTA -- The use of hormonal contraceptives was associated with a 24% reduction in risk of bacterial vaginosis in a study conducted by the Longitudinal Vaginal Flora Study Group.
"The significance of our findings is that a 24% reduction in risk of [bacterial vaginosis] may have a large impact on the general population in terms of adverse events such as preterm birth, miscarriage, pelvic inflammatory disease, and the susceptibility to sexually transmitted diseases," study investigator Margaret A. Hillier, Ph.D., told this newspaper.
A total of 3,620 women of reproductive age were recruited from family planning and gynecologic clinics in Birmingham, Ala., Dr. Hillier said at the annual meeting of the Society for Pediatric and Perinatal Epidemiologic Research.
All subjects underwent gynecologic examinations; laboratory tests quantified their vaginal microbial flora. Bacterial vaginosis (BV) was defined as a Gramstain score of 7 or higher. They also answered questions about their demographic characteristics, feminine health and hygiene behaviors, and gynecologic and sexual histories, said Dr. Hillier of the epidemiology branch of the National Institute of Child Health and Human Development, Bethesda, Md.
The study population was 80% black; among these women, the prevalence of BV was 44%. Among the remaining subjects, the prevalence was 24%.
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