AccessMyLibrary provides FREE access to over 30 million articles from top publications available through your library.
Create a link to this page
Copy and paste this link tag into your Web page or blog:
Elevated cytokine levels predicted preterm delivery in study; better positive predictive value than fFN.(News)
PHILADELPHIA -- Testing for a pair of cytokines gave better diagnostic accuracy than the standard fetal fibronectin test for premature delivery, based on a study with 115 deliveries.
Elevated levels of interleukin (IL)-6 and tumor necrosis factor (TNF)-[alpha] in cervicovaginal specimens had a better positive predictive value compared with fetal fibronectin (fFN) in a series that included 105 term pregnancies and 10 preterm deliveries, Dr. Ann M. Gronowski said while presenting a poster at the annual meeting of the American Association for Clinical Chemistry.
"These cytokines had performance characteristics that were similar to fFN, and they may serve as cost-effective markers," said Dr. Gronowski, a pathologist at Washington University in St. Louis. Tests for IL-6 and TNF-[alpha] cost about $10 each, compared with a price tag of $119 for the standard fFN assay.
Further study is needed to determine which cytokines have the best predictive value, she added.
The study included women with singleton pregnancies who had symptoms of preterm delivery between 24 and 34 weeks' ...
- Improving the positive predictive value of exercise testing in...
- Magazine article from: Heart Wong, Y.K. Dawkins, S. Grimes, R. Smith, F. Dawkins, K.D. Simpson, I.A. December 1, 2003 700+ words
...variables that can improve the positive predictive value of exercise testing in...resulting improvement in the positive predictive value. Results: Independently...between 0-11.5%. The positive predictive value for the remaining women...
- LCR testing for gonorrhoea and chlamydia in population surveys and other...
- Magazine article from: Sexually Transmitted Infections Zenilman, J.M. Miller, W.C. Gaydos, C. Rogers, S.M. Turner, C.F. April 1, 2003 700+ words
...However, even with highly specific tests, the positive predictive value (PPV) of such tests may be lower than desirable...prevalence populations is associated with a lower positive predictive value (PPV) and higher proportion of false positive...
- Positive predictive value of maximal posterior joint-line tenderness in...
- Magazine article from: Canadian Journal of Surgery Wadey, Veronica M.R. Mohtadi, Nicholas G.H. Bray, Robert C. Frank, Cyril B. April 1, 2007 700+ words
...of this prospective study was to determine the positive predictive value (PPV) of the point of maximal posterior joint...Results: We found a PPV of 60.0% and a negative predictive value of 62.5%, suggesting that maximal posterior...
- Low sensitivity, positive predictive value: low PAPP-A tied to poor pregnancy...
- Magazine article from: OB GYN News Sullivan, Michele G. April 1, 2004 700+ words
...Fetal Medicine. Although many of the associations are highly statistically significant, the sensitivity and positive predictive values for the individual outcomes are relatively low, said Dr. Dugoff, a coinvestigator for the First and...
- Assessing the predictive value of clinical complete response to neoadjuvant...
- Newspaper article from: Clinical Oncology Alert September 1, 2002 700+ words
...a pCR. That is, the positive predictive value of cCR = 25%. Among...designated pCR. Given the poor positive predictive value of cCR, even in the hands...MRI may not improve the positive predictive value of clinical assessment...
- Hepatopulmonary syndrome: prevalence and predictive value of various cut offs...
- Magazine article from: Gut Schenk, P. Fuhrmann, V. Madl, C. Funk, G. Lehr, S. Kandel, O. Muller, C. December 1, 2002 700+ words
...2] as the cutoff, the positive predictive value for a diagnosis of HPS was...had considerably higher positive predictive values (44%, 93%, and...Hg as the cut off, the positive predictive value increased to 1 00%. Dyspnoea...
- Study questions predictive value of ALT levels in hepatitis C patients.
- Newspaper article from: Hepatitis Weekly December 9, 2002 700+ words
...in France suggest that the predictive value of alanine aminotransferase...a score of at least F1 (positive predictive value [PPV], 99%) and 88...of at least F1 (negative predictive value [NPV], 35%) and 26...
- Predictive value of ambulatory blood pressure shortly after withdrawal of...
- Magazine article from: British Medical Journal Beltman, Frank W. Heesen, Wilfred F. Kok, Ronald H.J. Smit, Andries J. May, Johan F. Graeff, Pieter A. de Havinga, Tjeerd K. Schuurman, Frits H. Veur, Enno van der Lie, Kong I. Jong, Betty Meyboom-de August 17, 1996 700+ words
...and positive and negative predictive value of seated and ambulatory...the sensitivity and the positive predictive value eight weeks after withdrawal...specificity and negative predictive value were comparable for both...
- Variations in sensitivity, specificity and predictive value of a dietary fat...
- Magazine article from: Journal of the American Dietetic Association Caan, Bette Coates, Ashley Schaffer, Donna May 1, 1995 700+ words
...the sensitivity(1), specificity(2), and positive predictive value(3) of the instrument. We also examined the...to calculate sensitivity, specificity, and positive predictive value at each of the percentile cutoff points (18...
- The Rotterdam AMblyopia Screening Effectiveness Study (RAMSES): compliance and...
- Magazine article from: British Journal of Ophthalmology Juttmann, Rikard November 1, 2001 700+ words
...prevention programme and the positive predictive value (PPV) of the screening...possible. For amblyopia, the predictive value of a positive test result...prevention programme and the predictive value of positive screening test...
Source: HighBeam Research, Elevated cytokine levels predicted preterm delivery in study; better...