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Equal to women without fibroids: myomectomy did not harm IVF pregnancy success rates in study.(Gynecology)
RANCHO MIRAGE, CALIF. -- Patients who undergo surgery for leiomyoma appear to have the same chance for pregnancy success through in vitro fertilization-embryo transfer as do infertile women without fibroids, Dr. Eric Surrey reported at the annual meeting of the Pacific Coast Reproductive Society.
Most studies have concluded that submucosal and intramural leiomyoma negatively impact implantation and/or pregnancy rates in women undergoing in vitro fertilization-embryo transfer (IVF-ET).
The impact of precycle myomectomy in these patients had not been well investigated, however, so Dr. Surrey and his associates at the Colorado Center for Reproductive Medicine in Englewood, Colo., analyzed their results from a 2-year period.
The review assessed outcome in three groups of patients whose leiomyoma were diagnosed and/or evaluated during precycle ultrasound and hysteroscopic assessments conducted as part of the fertility work-up:
* Thirty-one patients with submucosal leiomyoma, who then underwent precycle hysteroscopic myomectomy.
* Twenty-nine patients with large submucosal leiomyoma with significant intramural extension or intramural leiomyoma that distorted or abutted the endometrial cavity, with
* Eight hundred ninety-six age-matched patients with none of the described lesions who also underwent fresh IVF-ET during the same time period.
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Source: HighBeam Research, Equal to women without fibroids: myomectomy did not harm IVF...