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Blunted response: black women may need more oral vitamin D.(Gynecology)

OB GYN News

| August 01, 2004 | Sullivan, Michele G. | COPYRIGHT 2004 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

NEW ORLEANS -- Black women may need higher doses of oral vitamin [D.sub.3] supplementation than white women to achieve optimal serum levels, Dr. Sonia Talwar said in a poster session at the annual meeting of the Endocrine Society.

"Black women's response to vitamin [D.sub.3] supplementation appears to be blunted, especially at higher doses," said Dr. Talwar of the State University of New York at Stony Brook. "Even at 50 [micro]g per day, we still weren't able to get all of these women up to what's considered a normal level for whites."

Oral vitamin [D.sub.3] supplementation is being studied as a way of optimizing vitamin D levels, but prior studies have been conducted primarily in white populations. Blacks have lower serum levels of vitamin D than whites because of their lower ability to synthesize the nutrient dermally.

Dr. Talwar tested the biochemical response to oral vitamin [D.sub.3] in 208 healthy postmenopausal black women aged 50-75 years. In the 3-year randomized, placebo-controlled trial, women ...

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