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PHOENIX, ARIZ. -- Selective reduction of triplets to twins or singletons was associated with later delivery and greater birth weight than in unreduced triplet pregnancies, according to results of a 10-year study.
"These findings support limiting the number of embryos transferred in in vitro fertilization or other assisted reproductive technologies by our reproductive endocrinology and fertility colleagues," Dr. John Williams III said at the annual meeting of the American Institute of Ultrasound in Medicine.
Between January of 1993 and June of 2003, he and his associates studied 74 women with triplets and 76 singleton controls who had chorionic villus sampling at 10-13 weeks' gestation. All patients were offered a detailed ultrasound examination at 18-20 weeks' gestation and again in the second and third trimesters, said Dr. Williams of the department of obstetrics and gynecology at Cedars-Sinai Medical Center, Los Angeles.
Of the 74 women with triplets, 10 continued with triplets, 45 reduced to twins, and 19 reduced to singletons. Each patient had from two to five ultrasound exams during the study.
The mean gestational age at delivery was 33 weeks for ...
Source: HighBeam Research, From triplets to twins, singletons: selective reduction associated...