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A woman who has a cesarean delivery in her first pregnancy may be at significantly increased risk of unexplained antepartum stillbirth in her second pregnancy.
That finding is based on a review of pregnancy discharge data from the Scottish Morbidity Record (1980-1998) and the Scottish Stillbirth and Infant Death Enquiry (1985-1998).
The study showed that of 120,633 singleton second births, there were 68 antepartum stillbirths among 17,754 women who had previously delivered by cesarean section, compared with 244 antepartum stillbirths among 102,879 women who previously delivered vaginally.
The absolute risk of unexplained stillbirth at or after 39 weeks' gestation was 1.1 per 1,000 women who had a previous cesarean section and 0.5 per 1,000 in those who had not, reported Dr. Gordon C.S. Smith of the University of Cambridge (England) and his colleagues (Lancet 362[9398]:1779-84, 2003).
The significantly increased risk was not attenuated by adjustment for maternal age, height, smoking, status, social deprivation, and interpregnancy interval or for key outcomes of the first pregnancy, including birth weight percentile, preterm delivery, and perinatal death. "It is possible that intentional or inadvertent ligation of major uterine vessels at the time of first ...
Source: HighBeam Research, Cesarean delivery may increase risk of a subsequent stillbirth: first...