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Women with myasthenia gravis are more likely than those without the disease to experience complications during pregnancy, a retrospective population-based study has shown.
Of the nearly 2 million women m Norway who gave birth between 1967 and 2000, 41% of the 79 women (127 live births.) with myasthenia gravis (MG) experienced obstetric complications, compared with 33% of the 1.9 million women without the condition.
Although the total rate of complications was significantly higher for the MG mothers, preterm rupture of membranes was the only single complication to occur significantly more often in the MG group (5.5% vs. 1.7%).
Of the women with MG, significantly more required interventions during birth (34% VS. 20%) or required delivery by cesarean section (17% vs. 9%), compared with the reference group (Neurology 61[10]:1362-66, 2003).
Complications were also ...