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COX-2 inhibitors advocated for dysmenorrhea: expert opinion.(Gynecology)
CHARLOTTETOWN, P.E.I. -- Although nonsteroidal anti-inflammatory drugs are currently the first-line treatment for primary dysmenorrhea, physicians should consider replacing them with cyclooxygenase-2 inhibitors, advised Dr. Fay Weisberg of the University of Toronto.
"COX-2 inhibitors are a new addition to the management of primary dysmenorrhea. They work as well as traditional NSAIDs but have a faster onset of action and potentially less side effects," Dr. Weisberg said at the annual clinical meeting of the Society of Obstetricians and Gynaecologists of Canada.
Studies show that NSAIDs provide effective pain relief in 64%-100% of patients with primary dysmenorrhea. But their main side effect, gastrointestinal intolerability, makes them difficult for some patients to take, even on a very short-term basis, and multiple dosing is also problematic, she said.
Even 1 week of NSAID use has been associated with GI ulcers, and the risk of GI ...
- Microwave diathermy treatment for primary dysmenorrhea.
- Magazine article from: Physical Therapy Vance, April R. Hayes, Sherrill H. Spielholz, Neil I. September 1, 1996 700+ words
...Microwave diathermy treatment for primary dysmenorrhea. Phys Ther. 1996;76:1003...intrauterine device).[1,2] Primary dysmenorrhea, the subject of this case report...several days each month.[2] Primary dysmenorrhea has been estimated to cause the...
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- Magazine article from: Physical Therapy Lewers, Deborah Clelland, Jo Ann Jackson, James R. Varner, R. Edward Bergman, Joan January 1, 1989 700+ words
...Nerve Stimulation in the Relief of Primary Dysmenorrhea Dysmenorrhea, or painful menstruation...1) primary and 2) secondary. Primary dysmenorrhea is defined as pain during menstruation...three days. [1] The causes of primary dysmenorrhea have not been defined spefically...
- Surgical Management of Primary Dysmenorrhea: Anything New?(Clinical report)
- Magazine article from: OB/GYN Clinical Alert December 1, 2007 700+ words
Surgical Management of Primary Dysmenorrhea: Anything New? Abstract...alone in the treatment of primary dysmenorrhea. Source: Juang C, et...study of 82 patients with primary dysmenorrhea who had been randomized...
- PDC Biotech GmbH, of Vienna, Austria, and Theratechnologies, of Montreal,...
- Newspaper article from: BioWorld International May 14, 2008 700+ words
...alpha receptor for use in preterm labor and primary dysmenorrhea (painful menstruation). In June 2006, Theratechnologies...and a topical formulation for the treatment of primary dysmenorrhea. Financial terms were not disclosed.
- Danggui-Shaoyao-San, a traditional Chinese prescription, suppresses...
- Magazine article from: Phytomedicine: International Journal of Phytotherapy & Phytopharmacology Hua, Y.Q. Su, S.L. Duan, J.A. Wang, Q.J. Lu, Y. Chen, L. December 1, 2008 700+ words
...of dysmenorrhea: Primary dysmenorrhea with menstrual pain...crucial role in primary dysmenorrhea, especially prostaglandin...elevated in women with primary dysmenorrhea compared with asymptomatic...cyclooxygenase (COX) protein is a rate...
- In Multiple Studies, Merck's Investigational COX-2 Specific Inhibitor Vioxx(TM)...
- Press release article from: PR Newswire March 18, 1999 700+ words
...single dose of the COX-2 specific inhibitor...hours after dosing. Primary dysmenorrhea, or painful menstruation...treatment prescribed for primary dysmenorrhea is naproxen sodium...the management of primary dysmenorrhea. COX-2 specific inhibitors...
- Pfizer Inc Receives Approval to Market New Oral COX-2 Inhibitor Bextra...
- Press release article from: PR Newswire May 19, 2003 700+ words
...tablets, the newest COX-2 selective inhibitor...arthritis (RA) and primary dysmenorrhea (painful menstrual...widest portfolio of COX-2 selective inhibitors...rheumatoid arthritis and primary dysmenorrhea," said Dr. Jack...Europe and Canada. "COX-2 selective inhibitors...
- COX-2 Expression in Oncology.
- Newspaper article from: Clinical Oncology Alert February 1, 2001 700+ words
...categorization of the relative roles of COX-1 and COX-2 as "housekeeping" and...be oversimplified. [1] Two COX-2 inhibitors are available in...osteoarthritis, acute pain in adults, and primary dysmenorrhea. Celecoxib (Celebrex) is approved...
- Novartis debuts COX-2 inhibitor Prexige in UK, its first European launch.
- Newspaper article from: Pharma Marketletter January 23, 2006 700+ words
...of safety concerns on other COX-2s, this could be optimistic...similar to some NSAIDs and COX-2 selective inhibitors but...knee replacement surgery and primary dysmenorrhea and had similar efficacy to...either an NSAID or a selective COX-2 inhibitor. Known as TARGET...
- CYCLOOXYGENASE-2 (COX-2) INHIBITORS.(Brief Article)
- Magazine article from: Southern Medical Journal SLAGLE, MARK A. August 1, 2001 700+ words
...be decreased with concurrent COX-2 inhibitor use. Concurrent...DRUG-FOOD INTERACTIONS The COX-2 inhibitors, especially...increase to 25 mg QD Acute pain or primary dysmenorrhea: 50 mg QD, should not exceed...OTHER POINTS OF INTEREST The COX-2 inhibitors should not be...
Source: HighBeam Research, COX-2 inhibitors advocated for dysmenorrhea: expert...