AccessMyLibrary provides FREE access to over 30 million articles from top publications available through your library.
Create a link to this page
Copy and paste this link tag into your Web page or blog:
Regular NSAID use tied to lower risk of breast Ca: Ibuprofen associated with 49% risk reduction after 10 years in older women: women's health initiative.(News)
WASHINGTON -- Women who take moderate amounts of NSAIDs weekly for at least 10 years may significantly reduce their breast cancer risk, according to a new analysis of data from the Women's Health Initiative.
Ibuprofen may be especially protective; it was linked with a 49% reduction in risk among women who took at least 200 mg per week for at least 10 years. In addition, the researchers observed a 21% decrease in risk among women who took at least 325 mg of aspirin per week. Acetaminophen--not known to block cyclooxygenase-2 (COX-2)--had no effect on breast cancer risk, which suggests that the primary mechanism of protection from NSAIDs relates to blocking COX-2, Dr. Randall E. Harris said at the annual meeting of the American Association for Cancer Research.
Children's aspirin (81 mg) and low-dose aspirin were not associated with any change in breast cancer risk.
"This isn't the first study of NSAIDs and breast cancer, but it is unique because it is a national sample of women and epitomizes the geographic profile of U.S. women in terms of ethnicity, education, and NSAID use," said Dr. Harris of Ohio State University, Columbus.
NSAIDs used in the study were limited to over-the-counter products and prescription products that were available before the development of selective COX-2 inhibitors.
Although the study focused on ibuprofen and aspirin, the researchers also found that the women who took the NSAIDs piroxicam, indomethacin, or naproxen for at least 5 years showed a 35% reduction in their risk of breast cancer. The study sample was not large enough to examine the specific effects of these individual NSAIDs, Dr. Harris said.
The study group consisted of 80,741 postmenopausal women, aged 50-79 years, who reported no personal history of breast cancer or any other malignancy at enrollment. The researchers collected baseline data on NSAID use and analyzed 1,392 histologically confirmed cases of breast cancer.
- Breast Cancer Survivor Jaclyn Smith Urges Women to Know Their Breast Cancer...
- Press release article from: PR Newswire July 10, 2007 700+ words
...Practitioners in Women's Health...National Breast Cancer Organization...to me as a woman to know about breast cancer risk factors...with other women," said...history raise a woman's overall...encourage all women to learn more about their breast ...
- Breast Cancer Research Stamp Funding the Fight to Find a Cure for a Decade;...
- News wire article from: AScribe Health News Service July 29, 2008 700+ words
...major ethnic group in this country, breast cancer is the most commonly diagnosed cancer in women, aside from skin cancer. Over...women in the U.S. are living with breast cancer, one million of whom have yet to...
- Breast cancer risk and immune responses in healthy women.(Clinical report)
- Magazine article from: Oncology Nursing Forum Park, Na-Jin Kang, Duck-Hee November 1, 2006 700+ words
...early identification of women at risk for breast cancer and developing appropriate...increased risk of developing breast cancer in women with a family history...detection of at-risk women and risk reduction for breast cancer. One step toward that...
- Breast cancer: a physician's view.(Preventing Cancer: What We Know Today)
- Magazine article from: Vibrant Life Glenn, Jerry May 1, 1995 700+ words
...developing breast cancer as compared...year-old woman. It remains...two third of women who develop breast cancer are not identified...like most women, you won...the risk of breast cancer. It is clearly in every woman's interest...
- Breast cancer update: what-really reduces your risk: the pill. Coffee. Sun....
- Magazine article from: Redbook Levine, Hallie October 1, 2002 700+ words
...higher rates of breast cancer, probably because...effects. When women in their 30s...have found that women who drank more...incidence of breast cancer. So go ahead...not linked to breast cancer. "The majority of women experience lumpiness...
- Breast Cancer Survivors Carry Optimistic Outlook on Life, Yet Lack Critical...
- News wire article from: Ascribe Higher Education News Service September 25, 2007 700+ words
...scientific advances, women are surviving breast cancer, remaining disease...majority (78 percent) of women who have had breast cancer are concerned about...recurrence. "For most women, a diagnosis of breast cancer has a significant impact...
- Breast cancer. (Letters to the Editor).
- Magazine article from: Townsend Letter for Doctors and Patients October 1, 2002 700+ words
...produced. With young women, there will be more...produced and more breast cancer. In this study with women aged 35 to 44, the...in a reduction in breast cancer deaths by more than...would be presumed that women in Portugal, Spain...
- Breast Cancer Activists Ask Public to Beware of Costly Fund-Raising Efforts.
- Newspaper article from: Knight Ridder/Tribune Business News September 29, 2002 700+ words
...days is "Think Before You Pink." Breast cancer activists are warning the public to...makers to car dealers, that put breast cancer's symbolic pink ribbon on a product...companies -- and never makes it to breast cancer causes, survivors say. The event...
Source: HighBeam Research, Regular NSAID use tied to lower risk of breast Ca: Ibuprofen...