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Proton-pump inhibitors also effective in nonerosive reflux disease. (Accounts for 50%-70% of Gerd Cases).

OB GYN News

| July 01, 2003 | Jancin, Bruce | COPYRIGHT 2003 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

SEATTLE--Proton-pump inhibitors, the therapeutic mainstay for gastroesophageal reflux disease, are also highly effective in the treatment of nonerosive reflux disease, according to a new metaanalysis.

That's good news, since nonerosive reflux disease (NERD) accounts for an estimated 50%-70% of total cases of gastroesophageal reflux disease (GERD). Prior to the metaanalysis, there wasn't really persuasive evidence that proton-pump inhibitors (PPIs) are effective in NERD. The great majority of data supporting PPI therapy in GERD come from clinical trials restricted to the minority of GERD patients having endoscopic evidence of erosive esophagitis, Dr. Ronnie Pass said at the annual meeting of the American College of Gastroenterology.

Indeed, after reviewing 107 studies on PPI therapy published or presented in ...

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Source: HighBeam Research, Proton-pump inhibitors also effective in nonerosive reflux disease....

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