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Underlying bleeding disorders implicated in half of all menorrhagia cases in adolescents. (Platelet Function Test).
PHILADELPHIA -- About half of adolescents with menorrhagia have an underlying bleeding disorder, according to a study with 30 patients at one institution.
A good way to assess bleeding disorders in these young patients is with a platelet function analyzer, such as the PFA-100, Dr. Victoria J. Davis said during the annual meeting of the North American Society for Pediatric and Adolescent Gynecology.
"I would use this test instead of bleeding time measurements" to screen patients for a bleeding disorder, said Dr. Davis, who is a pediatric and adolescent gynecologist at the Hospital for Sick Children in Toronto.
The PFA-100 measures the time it takes for a specimen of citrated whole blood in a capillary tube to block a membrane by forming a platelet plug, a parameter known as the closure time. Closure time is a measure of platelet aggregation and adhesion.
The PFA-100 is manufactured by Dade Behring Inc. Dr. Davis stated that she has no financial arrangements with Dade Behring, and this study was not sponsored by the company.
The study included 30 girls aged 11-16 years (mean age was 13) who were referred for assessment following a clinical diagnosis of menorrhagia.
All of the girls were ...
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