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COPYRIGHT 2003 International Medical News Group
BOSTON -- Partial interruption of antiretroviral therapy for HIV infection can help patients who have developed resistance to some, but not all, HIV-fighting drugs in a combination regimen, but the jury is still out on whether full treatment interruptions can improve HIV-specific immune responses, results of independent studies have shown.
Preliminary data on 20 HIV treatment-experienced patients who had become resistant to one therapeutic drug class in a combination regimen suggest that eliminating the resistant drug while continuing with the others can in some circumstances offer enough protection to keep the resistant virus in check and prevent the emergence of wild-type virus, Dr. Steven Deeks reported at the 10th Conference on Retroviruses and Opportunistic Infections.
This outcome minimizes the likelihood that a wild-type virus more "fit" than the resistant virus will emerge,...
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