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Risk of urge incontinence up more than twofold; stress incontinence rises fourfold.
NEW ORLEANS -- Hormone replacement therapy was associated with a more than twofold increase in risk of urge incontinence and an almost fourfold increase in risk of stress incontinence in postmenopausal women, according to a new analysis of data from the Heart and Estrogen/Progestin Replacement Study.
That finding builds on previous research suggesting that HRT does not seem to help women with incontinence. Of the nine previous randomized controlled trials of HRT for the treatment of incontinence, most showed no improvement in symptoms, and one showed a worsening of symptoms, Dr. Jody Steinauer said at the annual meeting of the American College of Obstetricians and Gynecologists.
In the current study, Dr. Steinauer and her associates attempted to determine whether HRT could prevent the development of incontinence in women without the disorder.
The study, which was awarded first prize at the meeting, focused on 1,208 HERS participants who reported no urinary incontinence at baseline. The women were an average of 66 years old and 18 years beyond the start of menopause.
A spokesperson for Wyeth, which manufactures various HRT products, noted in an interview that the HERS study subjects were considerably older than the average woman taking hormone therapy
"Most women taking hormone therapy are in their early 50's and at the beginning of menopause. The applicability of these findings to younger women is unknown," said Natalie de Vane, a spokesperson for Wyeth in ...
Source: HighBeam Research, HRT linked to increase in urinary incontinence. (Older Postmenopausal...