AccessMyLibrary provides FREE access to over 30 million articles from top publications available through your library.
Create a link to this page
Copy and paste this link tag into your Web page or blog:
Teens lose bone on DMPA, recover it after stopping use.(Gynecology)
Adolescent women who use the injectable contraceptive depot medroxyprogesterone acetate lose bone mineral density each year they are on the drug but appear to rapidly recover that loss when the drug is withdrawn, results of a prospective study suggest.
When counseling young women on birth control methods, physicians should consider DMPA's effect on bone mineral density (BMD).
"The potential loss of bone density is one consideration of the many that go into a women's choice of contraceptive method," said Delia Scholes, Ph.D., of the Center for Health Studies, Seattle, and her associates.
The researchers prospectively examined BMD in a cohort of 170 females aged 14-18. A total of 80 participants were using DMPA, and 90 were not. The DMPA-exposed teens were significantly more likely to be current smokers, to have been pregnant, have reached earlier menarche, and have a higher body mass index and body fat percentage (Arch. Pediatr. Adolesc. Med. 2005;159:139-44).
During the study, 61 of the DMP users discontinued the contraceptive, affording the opportunity to observe any subsequent changes in BMD.
The DMPA-exposed subjects were receiving the standard dose of 150 mg every 3 months. About 30% of them had received only 1 injection, 31% had received 2 or 3 injections, 21% had received 4-7 injections, and 18% had received at least 18 injections.
In the comparison group, 19% were using oral contraceptives at baseline.
- Investigational DMPA-SC treats endometriosis pain, curbs BMD loss.(Gynecology)
- Magazine article from: OB GYN News Finn, Robert January 15, 2005 700+ words
...formulation, called DMPA-SC (depot medroxyprogesterone...mineral density (BMD) and significantly...groups showed some BMD declines at the end...less for women taking DMPA-SC than for women...who'd been taking DMPA-SC saw their BMD return to pretreatment...
- Bone loss recoverable after stopping DMPA.(Women's Health)(depot...
- Magazine article from: Family Practice News Johnson, Kate July 1, 2005 700+ words
...documented complete recovery of BMD after DMPA discontinuation. "My speculation...we had been able to follow BMD for 3 or more years following DMPA discontinuation, it is likely...as after discontinuation of DMPA, BMD recovers. And we know from...
- Bone mineral density and DMPA: reassuring news.
- Magazine article from: Contraceptive Technology Update April 1, 2001 700+ words
...demonstrated a reduction in BMD in DMPA users. We have plans to do...found that long-term after DMPA use, BMD in former users is similar to...these studies suggest that the BMD declines seen in current DMPA users may be transient, and...
- Bone loss in teens on DMPA reverses after discontinuation.(Adolescent...
- Magazine article from: Internal Medicine News Sullivan, Michele G. July 1, 2005 700+ words
...any subsequent changes in BMD. The DMPA-exposed subjects were receiving...researchers determined that the DMPA users lost significantly more BMD at the hip (-1.81% vs...subjects who discontinued DMPA during the study, BMD increased. Their annualized...
- New research indicates recovery of bone density after teen DMPA use.
- Magazine article from: Contraceptive Technology Update April 1, 2005 700+ words
...indicated that women using DMPA for two years recorded a...in bone mineral density (BMD) of roughly 6%, compared...did the researchers find? DMPA users experienced an average...nonusers. Looking at spine BMD, DMPA users had a bone loss of...
- Be prepared to counsel on use of DMPA and bone health issues.
- Magazine article from: Contraceptive Technology Update February 1, 2005 700+ words
...However, concerns about BMD should not prevent use of DMPA in any appropriate user...published study show that when DMPA users were given a daily...estrogens, no loss of BMD was seen..sup.9 What about use of DMPA in adolescents? The contraceptive...
- Latest research sheds new light on DMPA's impact on bone health.
- Magazine article from: Contraceptive Technology Update October 1, 2004 700+ words
...bone mineral density (BMD). It is clear that use of DMPA reduces ovarian production...clear is whether use of DMPA causes any long-term impact on BMD or fracture risk. Look...contraceptives (OCs), DMPA, or nonhormonal contraception...
- DMPA use associated with bone density deficit in young adult women.
- Newspaper article from: Obesity, Fitness & Wellness Week December 4, 2004 700+ words
...forearm. In addition, DMPA users are likely to be...bone mineral density (BMD) was measured at the...family planning clinics. DMPA use was of at least 12...absorptiometry was used to measure BMD at the spine and hip...4% to -0.92%) in DMPA users, but no difference...
