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Seizure Rx rash: a lethal combo.(Clinical Rounds)

Publication: Skin & Allergy News

Publication Date: 01-MAR-05

Author: Mahoney, Diana
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COPYRIGHT 2005 International Medical News Group

STOWE, VT. -- What's the best way to get a dermatologist's attention? "Tell me you have a patient with a rash who also happens to have a seizure disorder," Dirk M. Elston, M.D., said at a dermatology conference sponsored by the University of Vermont.

The possibility that the patient might have a drug hypersensitivity syndrome or toxic epidermal necrolysis both--of which have been associated with anticonvulsant therapy--"is enough to make me stop what I'm doing and get right over," Dr. Elston said in a presentation on life-threatening dermatoses at the conference. Time is critical for such patients, as prompt recognition and appropriate treatment often hold the key to survival, he stated.

Toxic epidermal...

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