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BMD early in menopause predicts 10-year bone health: findings of this study support the role of bone density measurements in the first years after menopause.(Gynecology)
HARROGATE, ENGLAND -- A single bone mineral density measurement early in menopause is a strong predictor of future bone status in women not considered at risk for osteoporosis, a study has shown.
Despite various rates of bone mineral loss among individuals and measurement sites, baseline bone mineral density (BMD) measures of 766 women in the Danish Osteoporosis Prevention Study predicted 75% of the variation in lumbar spine BMD and 74% of femoral neck BMD variation over 10 years, Bo Abrahamsen, M.D., reported at the annual conference of the National Osteoporosis Society.
None of the women were taking hormone therapy or antiresorptive drugs. The baseline scans were acquired within 2 years of menopause.
Baseline lumbar spine T-scores greater than -1.2 were associated with a 90% negative predictive value for developing osteoporosis over 10 years, whereas a lumbar spine T-score greater than 0.5 had a negative predictive value of 100%.
A baseline femoral neck T-score greater than -1.7 had a 90% negative predictive value for femoral neck osteoporosis.
"No women developed femoral neck osteoporosis in the absence of baseline femoral neck osteopenia," said Dr. Abrahamsen of Odense (Denmark) University Hospital.
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Source: HighBeam Research, BMD early in menopause predicts 10-year bone health: findings of this...