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An alarming trend.(LETTERS)(Letter to the Editor)

OB GYN News

| February 01, 2005 | Tran, K.T. | COPYRIGHT 2005 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

The prevalence of methicillin-resistant Staphylococcus aureus (MRSA) and the trend toward widespread, worsening resistance with this particular organism pose a serious challenge to clinicians nationwide ("MRSA Emerging as Cause of Community-Acquired Infections, Studies Show" Dec. 1, 2004, p. 27).

As your article pointed out, the various types of infection associated with MRSA were observed in immunocompetent patients. Kevin Purcell, M.D., of Driscoll Children's Hospital in Corpus Christi, Tex., indicated that the rate of yearly community-acquired MRSA infections climbed dramatically from 9 to 459 cases during 1999-2003--a whopping 51-fold annual increase.

This begs the following question: What are the prevalence and incident rates of MRSA in community-acquired S. aureus infections (confirmed by positive specimen cultures) in the setting of that children's hospital?

Our health center on the Pine Ridge Reservation in South Dakota, which serves the Oglala Sioux tribe almost exclusively, has experienced a high level of MRSA in community-acquired infections.

In 2003, we saw four urine S. aureus isolates, two of which were MRSA; in the same year, we saw 209 nonurine S. aureus isolates (more than 98% from wound infections), 76 (36%) of which were MRSA and 23 (11%) of which were clindamycin resistant.

Fortunately, all MRSA isolates were sensitive to vancomycin and two sulfa drugs tested (rifampin and trimethoprim/sulfamethoxazole). For the first 9 months of 2004, there were five urine S. aureus ...

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