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New findings reported from University of Pennsylvania describe advances in aging.
"Reproductive aging of the male is characterized by decreasing fertility; however, factors that protect against reproductive aging in the male are largely unknown. Previous work has demonstrated that both female presence and aging have a dramatic effect on fertility in the male; yet, the effect of female presence on fertility in the aging male mouse is unknown," investigators in the United States report (see also Aging).
"The objective of this work was to determine the effect of long-term isolation or cohabitation with females on fertility in aged male mice. Male mice were housed with or without females until between 16 and 32 mo of age. Males were subjected to fertility tests at specific ages, after which serum and testes were isolated for radioimmunoassay and histological analysis. We show that male mice continuously housed with females remain fertile longer (similar to 20% of the reproductive lifespan) than male mice housed alone. Fertility became significantly reduced 6 mo sooner for males housed alone compared with males housed with females; however, the rate of decline was the same for males housed with or without females once fertility began to decrease. Testis weight decreased as the mice aged, and a nearly significant positive effect of female presence was observed. ...
- Primate reproductive aging; cross-taxon perspectives on reproduction.(Brief...
- Magazine article from: SciTech Book News December 1, 2008 700+ words
9783805585224 Primate reproductive aging; cross-taxon perspectives on reproduction. Ed. by...the collection concludes with a comparison of primate reproductive aging from lemurs to humans. Scholars of aging and reproduction...
- Transplacental exposure to 5-AZA-CdR affects behavior of male mice.
- Newspaper article from: Drug Week May 14, 2004 700+ words
...affects the sexual behavior of CD-1 male mice. According to recent research published...observed in 5-AZA-CdR in utero exposed male mice was a behavioral alteration, at gestation...behavioral test phase. "In utero exposed male mice resulted in diminished mating behavior...
- Increased serum corticosterone and glucose in offspring of...
- Magazine article from: Environmental Health Perspectives Cheng, Robert Y.S. Alvord, W. Gregory Powell, Douglas Kasprzak, Kazimierz S. Anderson, Lucy M. August 1, 2002 700+ words
...To test this hypothesis, we treated male mice with chromium(III) chloride, a preconceptional...To test this hypothesis, we treated male mice with chromium(III) chloride and mated...and Methods We injected NIH Swiss NCR male mice, 8 weeks old, from the Frederick Cancer...
- Aggressive behavior and serum testosterone concentration during the maturation...
- Magazine article from: Environmental Health Perspectives Kawai, Keisuke Nozaki, Takehiro Nishikata, Hiroaki Aou, Shuji Takii, Masato Kubo, Chiharu February 1, 2003 700+ words
...aggressive behavior and hormonal change in male mice. On gestation days 11-17, female...lt; 0.01) at 8 weeks of age in male mice exposed to bisphenol A at both the 2...aggression during the maturation process in male mice. Materials and Methods Animals. Pregnant...
- Effect of Verrucarin J Toxin on liver and kidney tissue of male...
- Magazine article from: The Texas Journal of Science El-Sawi Mahmoud, Nagwa M. El-Wassimy, Mohamed M. Youssef, Osama A. November 1, 2001 700+ words
...seeds were injected intraperitoneally to male mice for two, four, six and eight weeks...verrucarin J on the liver and kidney in male mice for different time periods to determine...performed on 160 normal healthy white male mice purchased from the animal house of Assiut...
- Male mice lacking the protein PICK1 mimic one cause of infertility in men.
- Newspaper article from: Obesity, Fitness & Wellness Week March 21, 2009 700+ words
...Technology, People's Republic of China, have now discovered that male mice lacking the protein PICK1 are infertile and that their condition...see also Journal of Clinical Investigation). In the study, male mice were found to have a low sperm count, with the remaining sperm...
- Aggression in male mice linked to 'girl power'.
- News wire article from: Asian News International October 5, 2009 700+ words
...networks of nerve cells in the brain that are associated with how male mice defend their territory, and found that these cells are controlled...findings did not appear to apply to sexual behaviour. While male mice reliably mate frequently with females, the oestrogen-treated...
- Germ cell transfer boosts fertility. (infertile male mice)
- Magazine article from: Science News Cowen, Ron November 26, 1994 700+ words
...Philadelphia now report transferring germ cells taken from virile male mice to the testes of infertile mice. Those cells matured to form...germ cells, including so-called stem cells, from fertile male mice. Next, they injected those cells directly into the seminiferous...
Source: HighBeam Research, New findings reported from University of Pennsylvania describe...