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Research reports from V. Traksmayra and co-authors provide new insights into alcoholism.
According to recent research from Clichy, France, "Chronic liver diseases, including cirrhosis, may develop in obese patients. Steatosis and non-alcoholic steatohepatitis (NASH) are risk factors for progression to fibrosis."
"To date, diagnosis of steatosis and NASH relies on liver biopsy. The aim of the study was to identify serum markers of steatosis and NASH in obese patients using SELDI-TOF ProteinChip. Eighty obese non-alcoholic patient candidates for bariatric surgery and devoid of hepatitis B and C infection were selected. Serum samples were collected before surgery and at 6 months after surgery for 33 of these patients. Wedge liver biopsy was performed at the time of bariatric surgery. Twenty-four serum samples from healthy blood donors served as controls. The protein profiles of each serum were assessed using SELDI-TOF ProteinChip technology and were compared according to liver histological lesions. Twenty-four obese patients (30%) had nonsignificant liver lesions, 32 (40%) had significant steatosis and 24 (30%) had NASH. Comparison of serum protein profiles according to liver lesions identified three peaks (CM10-7558.4, CM10-7924.2 and Q10-7926.9) the intensity of which significantly increased according to the severity of the liver lesions (steatosis and NASH) and returned to normal after bariatric surgery. None was correlated with either liver function tests or metabolic parameters. Identification using ...
- Vancomycin Loading Doses in Morbidly Obese Patients.
- Newspaper article from: Neurology Alert September 1, 2009 700+ words
...Vancomycin Loading Doses in Morbidly Obese Patients Abstract & Commentary Jessica...Clcr) does not apply to morbidly obese patients, given the lack of validation of such...of vancomycin observed in morbidly obese patients and to provide recommendations on loading...
- Obese patients are at increased risk for trauma complications.(Across...
- Magazine article from: Clinical Psychiatry News Zoler, Mitchel L. March 1, 2007 700+ words
PALM BEACH, FLA. -- Obese patients with critical injuries from blunt...for death after blunt trauma in obese patients, Dr. Michael F. Rotondo said...includes the highest percentage of obese patients, said Dr. Rotondo, chairman...
- Do you have strategies to care for obese patients?(Report)
- Magazine article from: ED Nursing January 1, 2004 700+ words
Do you have strategies to care for obese patients? EDs report numbers are increasing...part series on improving care of obese patients in the ED. This months story addresses...definitely have seen a rise in the number of obese patients in our ED, reports Stephanie J. Baker...
- Heavy costs; Hospitals pay high price to treat obese patients.(The Week in...
- Magazine article from: Modern Healthcare Piotrowski, Julie Romano, Michael December 22, 2003 700+ words
...treating or accommodating severely obese patients. Health officials say the costs are...seeing a greater number of severely obese patients-defined as overweight by at least...hospital staff to move and transport obese patients. More than 80% of the 69 hospitals...
- VIVUS Initiates Pivotal Phase 3 Trial in Obese Patients and Announces Qnexa...
- Press release article from: Business Wire November 9, 2007 700+ words
...study impact of Qnexa in morbidly obese patients MOUNTAIN VIEW, Calif. -- VIVUS...pivotal phase 3 studies of Qnexa in obese patients. The EQUIP study (OB-302) will enroll morbidly obese patients with Body Mass Index ("BMI...
- Triple drug therapy causes successful weight loss in obese patients.
- Newspaper article from: Obesity, Fitness & Wellness Week December 28, 2002 700+ words
...effective at promoting weight loss in obese patients with different eating patterns, according...The investigators identified five obese patients (body mass index, 34.5 to 38...effective and safe in a subpopulation of obese patients," concluded Anghelescu and associates...
- Knee Replacements in Obese Patients Are More Likely to Be Unsuccessful.
- Press release article from: PR Newswire August 11, 2004 700+ words
...Ill., Aug. 11 /PRNewswire/ -- Obese patients who undergo total knee replacement...only 88 percent of the replacements in obese patients were successful. "Nearly nine out...failure, while others have said that obese patients' lower level of activity may prevent...
- Atelectasis prevented during anesthesia in morbidly obese patients.
- Newspaper article from: Health & Medicine Week July 5, 2004 700+ words
...prevented atelectasis in morbidly obese patients. "Atelectasis caused by general...anesthesia is increased in morbidly obese patients. We have shown that application...efficacy of PEEP in morbidly obese patients to prevent atelectasis. Twenty...
Source: HighBeam Research, Research reports from V. Traksmayra and co-authors provide new...