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Reports summarize adenoma research from Osaka University, Medical Department.
"Tensin3 is a member of tensin family which is localized in focal adhesion. In our previous study, a high level of tensin3 mRNA expression was observed in the thyroid but not ill other tissues, thus, tensin3 gene was regarded as a novel thyroid-specific gene," scientists writing in the journal Experimental and Clinical Endocrinology & Diabetes report (see also Adenoma).
"The high expression level of tensin3 mRNA in normal thyroid tissue suggests some fundamental roles in thyroid functions. In fact, the expression level of tensin3 mRNA was low in most thyroid carcinomas and non-functioning thyroid follicular adenomas which do [lot produce thyroid hormone. In the present Study, we measured the expression levels of tensin3 mRNA in twelve functional adenomas and compared the results with those in normal thyroid tissues, adenomatous goiters and non-functioning thyroid follicular adenomas. Tensin3 mRNA was expressed abundantly in all twelve functional adenomas at almost the same level as in normal thyroid tissues and adenomatous goiters, while its expression was significantly lower in non-functioning follicular adenomas," wrote I. Maeda and colleagues, Osaka University, Medical Department.
The researchers concluded: "Considering these facts, all abundant expression of tensin3 mRNA is observed in tissues that produce thyroid ...
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Source: HighBeam Research, Reports summarize adenoma research from Osaka University, Medical...