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Findings from Indiana University, Medical Department advance knowledge in behavior.
"The basolateral amygdala (BL) is a putative site for regulating anxiety, where inhibition and excitation respectively lead to decreases and increases in anxiety-like behaviors. The BL contains local networks of GABAergic interneurons that are subdivided into classes based on neurochemical content, and are hypothesized to regulate unique functional responses of local glutamatergic projection neurons," investigators in the United States report (see also Emergency Preparedness).
"Recently it was demonstrated that lesioning a portion of the BL interneuronal population, those interneurons that express neurokinin receptors (NK1r), resulted in anxiety-like behavior. In the current study, these NK1r expressing cells of the BL are further phenotypically characterized, demonstrating approximately 80% co-expression with GABA thus confirming them as GABAergic interneurons. These NK1r interneurons also colocalize with two distinct populations of BL interneurons as defined by the neuropeptide content. Of the NK1r positive cells, 41.8% are also positive for neuropeptide Y (NPY) and 39.7% of the NK1r positive cells are also positive for cholecystokinin (CCK). In addition to enhancing the phenotypic characterization, the extent to which the NK1r cells of amygdala nuclei contribute to anxiety-like responses was also investigated. Lesioning the NK1r expressing interneurons, with a stable form of substance P ...
- Indiana University, Medical Department reports research in pancreas.(Report)
- Newspaper article from: Blood Weekly November 12, 2009 700+ words
...Fridell and colleagues, Indiana University, Medical Department (see also Pancreas...J.A. Fridell, Indiana University, School Medical...Transplantation, Indiana University, Medical Department. This article was...
- Indiana University, Medical Department reports research in...
- Newspaper article from: Blood Weekly May 21, 2009 700+ words
...Benson and colleagues, Indiana University, Medical Department. The researchers...contact M.D. Benson, Indiana University, School Medical...Cardiomyopathy, Surgery, Indiana University, Medical Department. This article was...
- Scientists at Indiana University, Medical Department report research in...
- Newspaper article from: Heart Disease Weekly March 15, 2009 700+ words
...Katz and colleagues, Indiana University, Medical Department. The researchers...3000, 10th St., Indiana University 410 W, Indianapolis...Disease, Medicaid, Indiana University, Medical Department. This article was...
- New catecholamin findings from Indiana University, Medical Department published.
- Newspaper article from: Biotech Week July 1, 2009 700+ words
...Hu and colleagues, Indiana University, Medical Department. The researchers...Purdue University, Indiana University, School Medical...Therapy, Treatment, Indiana University, Medical Department. This article was...
- Research conducted at Indiana University, Medical Department has updated our...
- Newspaper article from: Cancer Weekly September 22, 2009 700+ words
...Brabham and colleagues, Indiana University, Medical Department (see also Gynecology...J.G. Brabham, Indiana University, School Medical...Therapy, Treatment, Indiana University, Medical Department. This article was...
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- Newspaper article from: Obesity, Fitness & Wellness Week June 6, 2009 700+ words
...Zyromski and colleagues, Indiana University, Medical Department (see also Acute Pancreatitis...N.J. Zyromski, Indiana University School Medical, Dept...Therapy, Treatment, Indiana University, Medical Department. This article was...
- Scientists at Indiana University, Medical Department publish research in...
- Newspaper article from: Blood Weekly June 11, 2009 700+ words
...Benzion and colleagues, Indiana University, Medical Department (see also Glaucoma...contact A. Harris, Indiana University, School Medical...Ophthalmology, Perfusion, Indiana University, Medical Department. This article was...
- Data from Indiana University, Medical Department provide new insights into...
- Newspaper article from: Biotech Week April 29, 2009 700+ words
...Wei and colleagues, Indiana University, Medical Department (see also Ischemia...contact Y.S. Du, Indiana University, School Medical...Stem Cell Research, Indiana University, Medical Department. This article was...
Source: HighBeam Research, Findings from Indiana University, Medical Department advance...