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Fumaric acid esters emerging as treatment for severe psoriasis.(News)

Publication: Skin & Allergy News

Publication Date: 01-JUL-04

Author: Walsh, Nancy
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COPYRIGHT 2004 International Medical News Group

BUDAPEST, HUNGARY -- After many years of use in Germany, fumaric acid esters are now emerging onto the broader international dermatologic stage as a potential systemic therapy for severe psoriasis.

In a double-blind, placebo-controlled phase II study conducted at four centers in Poland, statistically significant, rapid improvements were seen in Psoriasis Area and Severity index (PASI) scores in a group of 144 patients with the chronic plaque, exanthematic guttate, erythrodermic, palmoplantar, or pustular types of psoriasis, Dr. A. Langner reported at an international symposium sponsored by the European Academy of Dermatology and Venereology.

Patients were required...

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