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Identifies candidates for treatment: CSF analysis yields clues to severe preeclampsia.(Obstetrics)

OB GYN News

| July 01, 2004 | Worcester, Sharon | COPYRIGHT 2004 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

FT. MYERS, FLA. -- Proteomic analysis of cerebrospinal fluid is useful for identifying biomarkers of severe preeclampsia, a study suggests.

The technology could help identify candidates for treatment, Dr. Errol R. Norwitz of Yale-New Haven Hospital reported at the annual meeting of the Society for Obstetric Anesthesia and Perinatology.

For the study, cerebrospinal fluid was obtained at the time of spinal anesthesia from seven patients with severe preeclampsia, eight patients with mild preeclampsia, and seven negative controls. A preeclampsia proteomic biomarker score was assigned to each specimen. Individual specimens were analyzed in blinded fashion, and scores were compared.

The proteomic biomarker score distinguished severe preeclampsia from mild preeclampsia and controls with 85.7% sensitivity and 100% ...

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Source: HighBeam Research, Identifies candidates for treatment: CSF analysis yields clues to...

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