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Open Channels.(treating cystic fibrosis)

The New Yorker

| May 04, 2009 | Groopman, Jerome | COPYRIGHT 2009 All rights reserved. Reproduced by permission of The Condé Nast Publications Inc. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

When Chrissy Falletti was born, in 1975, she seemed healthy, but soon her father, a physician in Youngstown, Ohio, and her mother, a nurse, observed that she was losing weight. At six weeks old, Falletti was admitted to Rainbow Babies & Children's Hospital, in Cleveland. As part of her evaluation, she underwent a sweat test--electrodes were strapped to her forearms, and her perspiration was collected on a thin paper filter. The test showed abnormally elevated amounts of chloride, a component of the salt in sweat, which indicated a diagnosis of cystic fibrosis. Falletti's mother quit her job to oversee her care. "No one in my family had cystic fibrosis, but my parents knew ...

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