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Flt-1 gene transfer suppresses gastric cancer peritoneal metastasis.

Cancer Gene Therapy Week

| July 19, 2004 | COPYRIGHT 2009 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2004 JUL 19 - (NewsRx.com & NewsRx.net) -- Flt-1 gene transfer suppresses gastric cancer peritoneal metastasis.

According to a study from Japan, "the prognosis of gastric cancer with peritoneal metastasis has not improved. Despite many promising studies, gene therapy has limited clinical application because of the lack of suitable vector systems to enable selective gene transduction to tumor cells. The aim of this study was to clarify whether gene therapy targeted to peritoneal mesothelial cells (PMCs) can inhibit peritoneal dissemination of gastric cancer."

"In vitro experiments showed that adenovirus expressing LacZ infected human omental tissue-derived…

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Source: HighBeam Research, Flt-1 gene transfer suppresses gastric cancer peritoneal metastasis.

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