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Nicotine patches aid in late pregnancy smoking cessation. (For the Highly Addicted, Highly Motivated).

OB GYN News

| March 01, 2002 | Walsh, Nancy | COPYRIGHT 2002 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

NEW ORLEANS -- Nicotine patches may help highly addicted but highly motivated pregnant women quit smoking, according to results of a study presented at the annual meeting of the Society for Maternal-Fetal Medicine.

Of 21 women who used the patch during an 8-week period in the third trimester, 8 stopped smoking through the time of birth, and 4 continued to refrain from smoking 4 weeks after delivery. Two women remained abstinent 1 year later, Dr. Paul L. Ogburn Jr. reported.

Before they entered the study, the women were smoking more than 15 cigarettes per day in their third trimester despite physician advice.

The study began with a 4-day inpatient stay. The women received nicotine patch therapy, 22 mg per 24 hours, for a total of 8 weeks. Serial ultrasound examinations and weekly nonstress tests documented fetal growth and well-being throughout the study. The women also were evaluated biochemically from enrollment through delivery using measurements of exhaled carbon monoxide, said Dr. Ogburn, director of the division of maternal-fetal medicine at the State University of New York at Stony Brook.

Gestational ages at delivery ranged from 36.3 to 41.1 weeks (median 39.1). Neonatal weights ranged from 2,400-4,400 g (median 3,405 g). None of the neonates were below the 10th percentile for weight.

Head circumference ranged from 32 to 38.1 cm (median 35), and median Apgar scores were 8 at 1 minute and 9 at 5 minutes. Three infants were ...

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