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Abortions and HER-2/neu overexpression. (No Link Seen).
SAN ANTONIO -- A history of induced abortion doesn't increase the risk of HER-2/neu overexpression in women with breast cancer, Dr. Angela Lanfranchi said at the annual breast cancer symposium sponsored by the San Antonio Cancer Institute.
She presented a retrospective study of 184 women diagnosed with breast cancer before age 60 years, all of whom had provided a detailed reproductive history before diagnosis of their malignancy.
Assessment of pathologic specimens showed that the rate of HER-2 /neu over-expression in the 30 women with a history of any induced abortions was virtually identical to that in the 88 patients with term pregnancies only, the 41 women with a history of one or more miscarriages but no induced abortions, and the remaining women who had never been pregnant, according to Dr. Lanfranchi of the Breast Cancer Prevention Institute in Poughkeepsie, N.Y
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