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Risk factors don't always predict osteoporosis. (Test Bone Density in All Women Over 65).
SAN FRANCISCO -- Screening detected osteoporosis but no risk factors for fracture in 14% of 7,154 postmenopausal women in a multinational study, Dr. Nelson B. Watts said in a poster presentation at the annual meeting of the American College of Rheumatology.
Physicians who ignore recommendations to test bone density in all women aged 65 years or older will miss this "unexpected osteoporosis" in a significant proportion of patients, according to Dr. Watts, director of the University of Cincinnati Bone Health and Osteoporosis Center.
In general, the majority of women with postmenopausal osteoporosis are not diagnosed until after they sustain a fracture. Some physicians choose to treat based on a clinical diagnosis of osteoporosis, he said.
"That's not adequate," Dr. Watts added. "Using that approach, you would be treating women who had risk factors for osteoporosis but who didn't have the disease, and you would be missing probably an equal number of women who had the disease but didn't have the risk factors."
Of the 2,558 women in the study in whom screening did detect osteoporosis, fully 38% had no risk factors for fracture. Among all women with risk factors for fracture, more than one-third did not have osteoporosis.
The findings came from a secondary analysis of data on women aged 65-80 years recruited into the IMPACT study (Improving Measurements of Persistence of Actonel Treatment), which was designed to assess whether patient compliance with osteoporosis treatment could be ...
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Source: HighBeam Research, Risk factors don't always predict osteoporosis. (Test Bone Density in...