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Bone drugs: threaten dental health.(NEWS FLASH: THE LATEST RESEARCH)(Brief article)
A University of Southern California School of Dentistry study concludes that some popular prescription medications for osteoporosis may cause death of cells (necrosis) in jawbone, resulting in pain, contributing to tooth loss, and significantly extending healing time after dental surgery.
Manufacturers of this class of drugs, which are known as bisphosphonates (e.g., Fosomax, Actonel, and Boniva), have asserted that only intravenous bisphosphonates may cause jaw necrosis while risk from oral forms is negligible. However, the study, published in The Journal of the American Dental Association, found that 4 percent of 208 patients taking oral forms of the medication experienced jaw necrosis. "Four percent is not negligible," says lead researcher Parish Sedghizadeh, DDS. The drugs have a 10-year half-life in bone tissue, so your dentist should be told about present or past bisphosphonate use.
In addition to getting sufficient calcium, ...
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