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Adefovir reduces fibrosis in precore mutant HBV. (Strain Does Not Produce E Antigen).(hepatitis B virus )
Publication: Internal Medicine News Publication Date: 15-FEB-02 Author: Mechcatie, Elizabeth
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COPYRIGHT 2002 International Medical News Group
Treatment with adefovir dipivoxil, an oral antiviral taken once a day, was associated with significant improvements in liver histology in a 48-week study of patients with precore mutant chronic hepatitis B virus infections.
In the multinational study of patients with this hepatitis B virus (HBV) strain, which does not produce the e antigen because of a mutation in the viral genome, 64% of the 123 patients who received 10 mg of adefovir once a day had improvements in liver histology...
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