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COPYRIGHT 2002 International Medical News Group
NEW ORLEANS -- First-trimester aneuploid screening using maternal age, biochemistry, and nuchal translucency measurement is "possible, accurate, and reliable," and should be more widely adopted, Dr. Ronald Wapner said at the annual meeting of the Society for Maternal-Fetal Medicine.
He based that comment on results of a multicenter study involving 8,215 women who underwent first-trimester screening using this approach. The detection rate for trisomy 21 was 85% with a false-positive rate of 9.4%. "A false positive cutoff of 5% still gave...
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