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HSV shedding found to be consistent, persistent.(NEWS)
WASHINGTON -- People infected with the herpes simplex virus shed virus no matter how long they have been infected or how frequently they have outbreaks, according to data from adults aged 18 years and older with newly acquired and long-term herpes infections.
Previous studies have suggested that herpes recurrences are more frequent within the first year after infection, and that viral shedding occurs on nearly 40% of days in patients with herpes simplex virus (HSV) infection for 6 months or less, said Clare A. Brennan and Cathy K. Heitman, Ph.D., of the infectious diseases medicine development center for GlaxoSmithKline in Research Triangle Park, N.C.
But the current study is the first to show a viral shedding rate on more than 50% of days in patients with new infections, they noted.
To study the natural history of viral shedding in patients with HSV-2, the researchers conducted a post hoc analysis of a placebo group comprising 69 patients who were part of a larger study that compared valacyclovir, acyclovir, and placebo.
The group included 27 patients who had had HSV-2 for 6 months or less, and 42 patients with HSV-2 for longer than 6 months and at least six recurrences per year. The new-infection group comprised 9 men and 18 women, and the established-infection group comprised 18 men and 24 women.
The researchers presented their results in a poster ...
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Source: HighBeam Research, HSV shedding found to be consistent, persistent.(NEWS)